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| Wed | May 15 | *Elite | Cowan - Guarantee | 21:00 | Woodstock FC Strikers | | German Canadian FC Bullets |
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| Wed | May 15 | RecDiv | Glencoe Community Centre | 19:00 | Glencoe Womens SC | | St. Marys SC Chargers B |
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| Wed | May 15 | 3 Div | Meadowcreek Lower | 19:00 | Ilderton Ignite | | Ingersoll SC |
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| Wed | May 15 | 1 Div | N. London Stadium | 20:45 | Whitecaps London U21 | | St. Thomas SC Reds |
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| Wed | May 15 | 3 Div | Windermere 2 | 18:30 | Norwest SC Bobcats | | Portuguese Club of London Thunder |
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| Thu | May 16 | 1 Div | BMO Centre Full Field | 18:30 | London-St. Thomas Croatia | | Sarnia FC |
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| Thu | May 16 | 3 Div | Greenway 3 | 18:30 | Southwest SC Storm | | German Canadian FC Eagles |
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| Thu | May 16 | RecDiv | Taxandria Soccer Complex #2 | 18:30 | Taxandria Soccer Club B | | Belmont SC Bulldogs |
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| Thu | May 16 | 3 Div | White Oaks North | 18:30 | Southend United SC Fusion | | West End SC Blues |
